Fourth seed Medvedev had won all his previous matches against Rublev in straight sets and it was no different at a scorching Rod Laver Arena on Wednesday.
World number one Carlos Alcaraz sailed into the Paris Masters third round with a 6-4, 6-4 win over Yoshihito Nishioka but Rafael Nadal and Daniil Medvedev both slumped to surprise losses on Wednesday.
'The Laver Cup next week in London will be my final ATP event. I will play more tennis in the future, of course, but just not in Grand Slams or on the tour.'
Rafael Nadal withdrew from the Indian Wells tournament on Saturday with a knee injury, shortly before his eagerly-awaited semi-final clash with great rival Roger Federer.
Drained Medvedev pulls out of home tournament in Moscow
The 22-year-old, 6ft 6in Russian, already the owner of two indoor hard court titles this year, moved one step away from the biggest title of his career at the Bercy indoor arena, crushing his Austrian friend in 70 one-sided minutes.
As a sporting spectacle Alcaraz and Djokovic matches have delivered on every level and would be worthy of the Big Apple spotlight.
Victory over Medvedev meant Alcaraz became the youngest man to win the Indian Wells and Miami Open titles, a feat dubbed the 'Sunshine Double'.
Second seeds Rohan Bopanna and Aisam-ul-haq Qureshi survived a scare before diffusing the challenge of Mahesh Bhupathi and Denis Istomin in the quarter-finals of the ATP 500 Dubai Duty Free Championships on Thursday.
'Everybody knows that they could wait a little bit, no? It was an unfortunate decision.'
Roger Federer will make his only appearance on clay this season at Roland Garros, his agent said. The Swiss skipped the entire claycourt season in 2017 and 2018 and last year played only two tournaments on the surface before arriving in Paris for the French Open.
Indian Davis Cupper Yuki Bhambri clinched his first doubles title of the season with partner Adrian Menendez-Maceiras, following a nerve-wracking win in the rain-hit final of the ATP Challenger event in Karshi, Uzbekistan on Saturday.
World No 1 Carlos Alcaraz fended off in-form American Tommy Paul to reach the Cincinnati Open quarter-finals on Thursday
It's a historical tie, we will benefit from India team's visit: Pakistan tennis fraternity
Rafael Nadal warmed up for the French Open with a battling 7-5, 1-6, 6-3 win over world number one Novak Djokovic as the Spaniard claimed a record-extending 10th Italian Open title in Rome on Sunday in the latest chapter of their rivalry.
Japan's Kei Nishikori will meet Spain's Feliciano Lopez in the final of the US National Indoor Tennis Championships after besting Australian Marinko Matosevic in the semi-finals in Memphis on Saturday.
India's Rohan Bopanna and his Romanian partner Florin Mergea reached the semi-finals of the ATP World Tour Finals with a straight sets win at London's O2 Arena on Tuesday.
Sinner has made the most of a favourable draw at the grasscourt major this year
World No. 1 Novak Djokovic has applied for special permission to enter the United States to participate in the ATP Masters 1000 events.
India's number one tennis player Sumit Nagal is left with less than Rs one lakh in his bank account and a morose feeling of not leading a good life.
Novak Djokovic is returning to the US for the first time in two years after being denied entry due to being unvaccinated for COVID-19.
Indian qualifier Sanam Singh brushed aside the challenge of Germany's Nils Langer even as Saketh Myneni failed to recreate the magic of last week as he bowed of the ATP Challenger event in Knoxville, USA.
The two standout performers will meet after 21-year-old Greek debutant Tsitsipas eclipsed six-times champion Roger Federer 6-3, 6-4 and Austrian Thiem dispatched defending champion Alexander Zverev 7-5, 6-3.
World No 2 Djokovic, who received a first-round bye, broke his opponent's serve four times to extend his winning run to 19 matches.
Top seed Novak Djokovic produced a stellar display to sweep aside Croatian Marin Cilic 6-3, 6-4 in the final of the ATP 250 Tel Aviv Open on Sunday and clinch his third title of the season.
'There is so much excitement brewing about Wednesday's Alcaraz and Rune quarter-finals showdown -- it could well be a juicy foretaste of things to come.'
Novak Djokovic used a dizzying array of drop shots to make short work of Karen Khachanov at the Dubai Open on Thursday, reaching the semi-finals with a dominant 6-2, 6-2 win over the Russian seventh seed.
Juan Martin del Potro, beaten in his six previous meetings with Roger Federer this year, turned the tables on the world number one to win a memorable Basel ATP final on Sunday.
World number one Rafael Nadal made light work of Greek teenager Stefanos Tsitsipas to win the Barcelona Open final 6-2, 6-1 on Sunday, lifting the trophy for a record-extending 11th time.
Kazahk Bublik powers past Zverev in straight sets to reach Halle final
South Korea's Chung Hyeon said he hopes the shot clock being tested out at the inaugural Next Gen ATP Finals in Milan will become a regular feature on the Tour because it allows him to clean his spectacles without worrying.
Indian tennis ace Leander Paes and Andre Begemann of Germany went down to local hero Denis Istomin and Mikhail Elgin of Russia in the doubles finals at the ninth edition of the $125000 Tashkent ATP Challenger at the Olympic Tennis School in Tashkent on Friday.
Novak Djokovic, the world number one ranked men's player, has reiterated his stand about freedom of choice over taking the COVID-19 vaccine as suspense grows over his participation at the Australian Open in January.
Iga Swiatek's maiden triumph at the US Open extended her lead to almost twice as many points as the second-ranked Ons Jabeur
IMAGES from Day 5 of the French Open at Roland Garros in Paris on Thursday.
It will be the second consecutive final for Paes and Angel, who also reached the final at Montrrey Challenger last week, ending runners-up to Jeevan Nedunchezhiyan and Marcelo Arevalo.
World number one Carlos Alcaraz marked his return to action following his Wimbledon triumph with a battling 4-6, 6-4 (10-8) win over David Goffin in their Hopman Cup clash on Friday but could not prevent Spain from losing 2-1 to Belgium.
Novak Djokovic is capable of extending his record for holding the men's World No. 1 ranking for most weeks to 400, said Russia's Daniil Medvedev who will climb up to a career-best ranking of second on Monday.
Images from Day 3 of the US Open, at Flushing Meadows, New York.
Goffin stuns Federer to reach London final